<script>
function test(){
alert('ss');
}
</script>


<div style="width: 100px; height: 100px; border: black 1px solid;" onClick="test();"></div>

<script>
function simulateClick(x, y) {
var el = document.elementFromPoint(x, y);
el.innerHTML = 'sss';
alert('ss');
var evt = document.createEvent("MouseEvents");
evt.initMouseEvent("click", true, true, window,
1, 0, 0, x, y,
false, false, false, false, 0, null);

el.dispatchEvent(evt);

}
</script>


<a href="" onclick="javascript: simulateClick(250, 250);">111</a>