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<!DOCTYPE html>
<html>
<head>
<title>Untitled</title>
<meta charset="utf-8">
<style type="text/css"> .red{
color: #FF0000;
}
</style>
<script src="https://ajax.googleapis.com/ajax/libs/jquery/1.12.4/jquery.min.js"></script>
<script>
$(function() {
$('div:contains("Спам")').filter(function() {
return !$(this).children().length
}).addClass("red")
});
</script>
</head>
<body>
<div>
<div> test
<div>Спам</div>
</div>
</div>
</body>
</html>