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<!DOCTYPE html>
<html>
<head>
<title>Untitled</title>
<meta charset="utf-8">
</head>
<body>
<textarea id="tmp">123456RTYUQWASDF1223ZXXC122345</textarea>
<script>
var t = document.getElementById('tmp'), tmp;
t.addEventListener('input', function() {
clearTimeout(tmp);
tmp = setTimeout(_ => t.value = t.value.replace(/\s/mig, '').match(/.{1,2}/g).join(' '))
}, 100)
</script>
</body>
</html>