<input type='radio' name='top' value='top1' onchange="check();"/> top 1<br />
<input type='radio' name='top' value='top2' onchange="check();" /> top 2<br />
<input type='radio' name='bottom' value='bottom1' onchange="check();" /> bottom 1<br />
<input type='radio' name='bottom' value='bottom2' onchange="check();" /> bottom 2<br />
<input type='submit' value='Отправить' name="submit" disabled="disabled"/>
<script>
function check() {
var top1 = document.getElementsByName('top')[0],
top2 = document.getElementsByName('top')[1],
bottom1 = document.getElementsByName('bottom')[0],
bottom2 = document.getElementsByName('bottom')[1],
submit = document.getElementsByName('submit')[0];
if ((top1.checked || top2.checked) && (bottom1.checked || bottom2.checked))
submit.disabled = '';
else
submit.disabled = 'disabled';
}
</script>