#save {
background-color: blue;
}
#save:disabled {
background-color: red;
}
var select = $('select');
var save = $('#save');
select.change(function() {
for(var i = 0; i < select.length; i++) {
if(select[i].value === 'F200') {
return save.prop('disabled', true);
}
}
save.prop('disabled', false);
});