Ruslan_xDD,
Sav2907,
<!DOCTYPE html>
<html>
<head>
<title>Untitled</title>
<meta charset="utf-8">
<style type="text/css">
#save {
background-color: blue;
}
#save:disabled {
background-color: red;
}
</style>
</head>
<body>
<script src="https://ajax.googleapis.com/ajax/libs/jquery/3.2.1/jquery.min.js"></script>
<button id="save" >СОХРАНИТЬ</button><br>
<select id="name1">
<option selected></option>
<option value="F100">F100</option>
<option value="F200">F200</option>
<option value="F300">F300</option>
</select><br>
<select id="name2">
<option selected></option>
<option value="F100">F100</option>
<option value="F200">F200</option>
<option value="F300">F300</option>
</select><br>
<select id="name3">
<option selected></option>
<option value="F100">F100</option>
<option value="F200">F200</option>
<option value="F300">F300</option>
</select>
<script>
$('select').on('change', function(){
var name = document.querySelectorAll("[id^='name']");
var a = false;
for (var i = 0; i< 3; i++) if(name[i].value == 'F200') {a = true; break};
$("#save").prop("disabled", a)
//.css({"background-color": a ? "red" : "blue"});
});
</script>
</body>
</html>